THE RADIATION EFFECT ON BLOOD CELLS IN CANCER PATIENTS WHO HAVE UNDERGONE EXTERNAL RADIATION THERAPY- ANALYTICAL STUDY

Published: 2025-06-04

Abstract

Normal leukocytes count ranges from 4500-11000, Platelets 150,000-400,000/mm3 and Hemoglobin level male: 13.5-17.5 g/dL, female: 12.0-16.0 g/dL. External beam radiation therapy is a treatment using high-energy ionizing radiation is part of cancer treatment methods to control and kill malignant cells at the treatment site. However, normal cells and cancer cells are affected at the same time, the effect depends on the sensitivity of the Cells as well as the value of the dose deposited to the area. This study is aimed at assessing only changes in WBCs, Plts and Hgb level. PATIENTS AND METHODS:  Forty-two patients from the University Hospital radiotherapy department in Tripoli, Libya, were included in this study from April to August 2024. The information related to the study was collected from the archive unit of the department after approval to conduct the study. RESULTS:  Out of the 42 patients, 26 (61.90%) females and 16(38.1%) males, the median age was 51.4years the age group has diversified (17 to 82) years. According to the treatment sites we classified them into eight groups the most common cancer was breast cancer accounting for 20 (47.6%), 6(14.28%) of cases were head and neck, 4(9.52%) larynx cancers, 4(9.52%) lymphoma cancer, 2(4.76%) lung, 3(7.14%) prostate, 2(4.76%) cervix and 1(2.38%) rectum. We found a statistically significant (P<0.10) reduction in total (WBCs) count, Plts counts and  Hgb level  when compared the results of Pre RT to Post RT. CONCLUSION: Leukocytes, platelets and hemoglobin level, are the main hematological indicators that predict the response rate to treatment, severity of the disease. The effectiveness and progress of radiation therapy can be estimated in this way.

Keywords: Effect radiotherapy criteria hematology cancer patients

How to Cite

Nureddin. A. S. Musa, & Samia. A. Alkdrawe. (2025). THE RADIATION EFFECT ON BLOOD CELLS IN CANCER PATIENTS WHO HAVE UNDERGONE EXTERNAL RADIATION THERAPY- ANALYTICAL STUDY. Bani Waleed University Journal of Humanities and Applied Sciences, 10(2), 573-581. https://doi.org/10.58916/jhas.v10i2.814

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Author Biography

  • Nureddin. A. S. Musa, General Department, Faculty of Biotechnology, University of Jfara, Jfara, Libya

    CURRICLUM VITAE

    TO WHOM IT MAY CONCERN

    1

    PERSONAL INFORMATION:-

    ·         Name: Nureddin Ahmed.S. Musa

    ·         Nationality: Libyan

    ·         Marital Status:  Married

    ·         Address: Tripoli - Libya

    -         Contact points: Phone:- 0915194767, 0925194767

    -         Email:-nureddine2001@yahoo.com.,  nureddin.a.s.musa@aju.edu.ly

    -         Affiliation: College of Biotechnologies, Aljfara University- Libya

    2

    EDUCATIONAL PROFILE:-

    ·         BSc  degree College of medical technology Radio-diagnostic and therapeutic year 1992.  

    ·         PG. Certificate in Radiation therapy, year 2001.

    ·         MSc degree Medical Physics year 2017.

    ·         PhD degree Medical Physics year 2021.

    3

    CLINICAL EXPERIENCE PROFILE:-

    ·         Certificate ( Quality Assurance and Quality control procedures for radiology) year1997 Kenya - IAEA.

    ·         Certificate (Regulatory authorization and inspection of Radiation Sources in medical practices) 2003 Tripoli – IAEA.

    ·         Certificate (Radiation therapy practice, Dosimetry) 2006., Cancer institute in Morocco- IAEA.

    ·         Certificate (Medical Physics dosimetry and QA Radiation Therapy 2010., IAEA cancer institute in Morocco.

    ·         Certificate (Applications of radioisotopes, Radiation Protection and Radiation Safety) Middle Eastern Regional Radioisotope Center for the Arab Countries year 2012.

    4

    FUNCTIONAL TAKS:-

    ·         Member of Radiation therapy department since 1995 - 2012 as Radiotherapist with full responsibility.

    ·         Member of Radiation Protection Committee 2012 - 2018, Tripoli Central Hospital.

    ·          Member of European Society of Radiology since 2012- 2024.

    ·         Head of National Project, Cooperation with the International Atomic Energy Agency, LIB6009 ( 2014-2017).

    ·         Member of Teaching staff, Undergraduate, Graduate- Libyan Universities since 2018- 2025.

    5

    PUBLICATIONS:-

    ·         Seven  Papers has been  Published since 2016 -2024.

    6

    PERSONAL SKILLS

    ·         Organization, management and leadership.

    ·         Time Management.

    ·         Effective communication with others.

    ·         The use of computer applications ( statistical analysis).

         

    You're sincerely

     

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