Relationship between parvovirus B19 infection and anemia among hemodialysis, Libya

Dr. Musbah Emhamed  Almbsuot

doi:10.58916/jhas.v7i3.617

Authors

Dr. Musbah Emhamed Almbsuot Medical laboratory department , Faculty of Medical Technology, Alzzaytuna university Author

DOI:

https://doi.org/10.58916/jhas.v7i3.617

Keywords:

parvovirus B19 .hemodialysis . anemia .ELISA

Abstract

Parvovirus B19 is considered one of the animal viruses that infect humans, as the virus infect a mature red blood cells and leads to many problems, especially in individuals with low immunity , including hydrops fetals in pregnant women and anemia, in addition to arthritis and other problems. In dialysis patients, as a result of frequent dialysis and sometimes blood transfusions, it makes them susceptible to infection with the virus through various ways of transmission too.

Aim : The aim of the study is to try to find a relationship between infection with the virus and anemia

Materials and methods: A total of 80 samples include 54 males and 26 females of dialysis patients were collected from several centers in Libya during the period the end of December 2021, and early March 2022 Randomly. It consists of 5 ml of blood divided into two parts. First, 1 ml of whole blood is analyzed to obtain the hemoglobin rate. It is recorded in the questionnaire prepared for this purpose, after which the rest of the sample is subjected to Centrifugation to obtain the serum for the purpose of conducting the ELISA test. The samples were kept at a temperature of -20 until analyzes.

Results: This study found that the parvovirus B19 was widespread in Libyan hemodialysis patients. It also revealed varying levels of IgM and IgG antibodies to B19. In contrast, IgG was 48.8% (39/80) and IgM was 11.3% (9/80). 48.8% of patients were found to be normal, while 51.3%( of patients had anemia. Although 22/41 (53.7%) patients had anemia and infected by B19, statistically The study discovered a significant relationship between anemia and acute infection (IgM), but not a significant relationship between chronic infection and anemia (IgG).

Conclusions: The study concluded that there was a connection between anemia and B19, and that B19 was common in hemodialysis.

Recommendations: Confirmation of B19 testes inquiry should be done in hemodialysis, particularly in blood transfusion cases.

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