Prevalence and Hematological Effects of Helicobacter pylori Infection in Tobruk, Libya: A Cross-Sectional Study
DOI:
https://doi.org/10.58916/jhas.v10i1.696الكلمات المفتاحية:
Anemia, helicobacter pylori, hematological effects، prevalence, Libya, Tobrukالملخص
This study aimed to determine the prevalence of Helicobacter pylori (H. pylori) among the residents of Tobruk in October 2023. Samples were collected from the Ibn-Rushed Laboratory, and 362 cases were statistically analyzed for bacterial infection. The results showed that 174 out of 362 cases (48.06%) were positive for H. pylori, 178 cases (49.17%) were negative, and 10 cases (2.76%) were borderline. Furthermore, the study investigated the effect of H. pylori infection on hematological parameters using 50 samples (30 females and 20 males). The results revealed that males showed a decrease in mean corpuscular hemoglobin (MCH) (45%), hemoglobin (HGB) (55%), and plateletcrit (PCT) (40%), along with an increase in mean platelet volume (MPV) (45%) and PCT (50%). In females, MPV and PCT showed a mean increase of 83.3%, with other blood values remaining within the normal range. This study concluded that the population in the Tobruk region has a considerably high frequency of H. pylori infection, with significant effects on hematological parameters.
التنزيلات
المراجع
Abdallah, M., et al. (2021). The Prevalence of Helicobacter pylori in Sirte: A Survey among University Students. Libyan Journal of Infectious Diseases, 17(1), 89-95.
Allagoa, D. M. (2020). White Blood Cell Count and Neutrophil Response in Helicobacter pylori Infection: A Nigerian Study. Journal of Immunological Research, 9(5), 314-322.
Al-Rashed, M. (2022). Helicobacter pylori and its hematological impacts in the Tobruk region: A preliminary study. International Journal of Infectious Diseases, 118, 42-49.
Choi, J. H., Lim, Y. J., & Jang, K. H. (2024). Recent advancements in the diagnosis of Helicobacter pylori infection. Journal of Clinical Gastroenterology, 58(5), 372-385.
Hussen, Z., et al. (2023). The Prevalence of Helicobacter pylori Infection among Students in Iraq. BC Infectious Diseases, 13, 155.
Johnson, E. C., Walker, K. J., & Roberts, M. T. (2023). The link between Helicobacter pylori infection and iron deficiency anemia: A review. Gastroenterology Research and Practice, 2023, Article ID 4712934.
Keramati, A. (2020). The Hematological Effects of Helicobacter pylori Infection in Libyan Patients. Libyan Medical Journal, 4(2), 64-70.
Kibru, M. (2020). Hematological Changes in Helicobacter pylori-Infected Ethiopian Patients. International Journal of Infectious Diseases, 18(3), 233-238.
Kim, M. Y., Park, H. J., & Cho, D. H. (2022). Mechanisms of Helicobacter pylori survival in the acidic stomach environment. Microbial Pathogenesis, 162, 105367.
Lee, J. H., Choi, M., & Kwon, Y. S. (2021). Pathogenesis of Helicobacter pylori and its clinical significance in gastric diseases. Journal of Clinical Microbiology, 59(3), 499-512.
Mahrazi, S., et al. (2020). Prevalence of Helicobacter pyllori among University Students in Saudi Arabia. Journal of Medical Microbiology, 24(9), 1345-1351.
Mezmale, L., et al. (2020). Prevalence and Serological Profile of Helicobacter pylori in Tarhuna. Journal of Infectious Diseases, 13(5), 189-196.
Mohammad, S., et al. (2020). Helicobacter pylori Seropositivity in Benghazi Teaching Hospital. Libyan Journal of Gastroenterology, 6(2), 58-63.
Mwafy, M. H. (2020). Hematological Changes in Helicobacter pylori Infection in Palestinian Patients. Gastroenterology Research and Practice, 22(4), 110-115.
Nami, A., et al. (2020). Helicobacter pylori Infection in Asymptomatic University Students: A Study in Kasr Khiar, Libya. Libyan Journal of Medical Research, 18(2), 112-118.
Park, Y. K., Jeong, S. H., & Kang, M. S. (2021). Advancements in diagnostic techniques for Helicobacter pylori infection. Digestive Diseases and Sciences, 66(9), 2960-2969.
Shaldoum, R. A. (2021). Anemia Associated with Helicobacter pylori Infection: A Review. Journal of Clinical and Diagnostic Research, 10(6), OE01-OE04.
Wang, H. J., Zhang, Y., & Liu, Z. (2020). The broader health implications of Helicobacter pylori infection: Extra-gastric manifestations. Clinical Reviews in Allergy & Immunology, 58(2), 218-227.