Structural and electronic modulation of TiO₂/Tiopronin hybrid nanoparticles: correlation with antibacterial activity under sunlight

Abstract

In this study, we prepared TiO₂ nanoparticles and nanoparticles (TiO₂/Tiopronin) by Laser ablation. The nanoparticles were measured using transmission Electron Microscopy (TEM), Field emission scanning electron microscopy (FE-SEM), and x-ray diffraction (XRD). the results of X-Ray diffraction show that TiO₂ nanoparticles have a very small size reached (20.17) nm while the nanoparticles (TiO₂/Tiopronin) have (53) nm and this consider the lowest diameter obtained in this method while the results by TEM showed the size of TiO₂ nanoparticles is (17) nm and the size of the nanoparticles (TiO₂/Tiopronin) is (49) nm, in this work, we studied the effect of the sunlight with TiO₂ nanoparticles and nanoparticles (TiO₂/Tiopronin) on Pseudomonas Aeruginosa isolated from burn infections and we noticed that the nanoparticles appear a higher inhibition towards the Pseudomonas Aeruginosa more than the inhibition by sunlight and TiO₂ nanoparticles alone. So, we can say that we succeeded in preparing useful nanoparticles (TiO₂/Tiopronin) by using a simple green method with the lowest cost and using it to inhibit the Pseudomonas Aeruginosa that cause Burn Infections.